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Alkalinization of urine hastens phenobarbital excretion, but dialysis and hemoperfusion are more practical and lead to much less troublesome alterations in electrolyte equilibrium. Should the individual has chronically abused sedatives, withdrawal reactions may be manifest adhering to acute overdose.This drastically facilitated our analyze on drug-

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phenobarbital will lower the extent or influence of stiripentol by affecting hepatic enzyme CYP1A2 metabolism. Stay away from or Use Alternate Drug. If unable to prevent coadministration of stiripentol with sturdy CYP1A2 inducers, raise stiripentol dose.No dosage adjustment for ondansetron is usually recommended for patients on these medicines.Smal

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